A Young, Immunocompetent Woman with Small Bowel and Hepatic Mucormycosis Successfully Treated with Aggressive Surgical Debridements and Antifungal Therapy

Figure 1

(a) Portal venous phase contrast-enhanced CT shows several small hypoattenuating lesions with slight peripheral enhancement. (b) Two days later, CT shows progression with multiple large hypoattenuating lesions in both the left and right lobe of the liver, suggestive of liver abscesses. (c) Time course of LAmB dosage, serum posaconazole, and serum bilirubin levels. Taking into account the long serum terminal half-life and mean residence time in the liver tissue of LAmB, the graph suggests that LAmB was an important contributor to the cholestasis and hepatotoxicity (as measured by total bilirubin levels) observed in our patient.