Case Report

Parainfluenza 3 Respiratory Infection Associated with Pericardial Effusion in a Very Low Birthweight Infant

Table 1

Diagnostic tests performed.

TestResults

Blood test before the diagnosis of the pericardial effusion, during sudden clinical deteriorationLeukocytosis 15.08 cells/mm3 (5–14.5 cells/mm3; 75% lymphocytes, 12% neutrophils); hemoglobin 12.5 g/dl (10–13 g/dl) and platelet count 280/mm3 (250–450/mm3). ALT 203 U/L (6–50 U/L), AST 180 U/L (35–140 U/L), C-reactive protein (CRP) 3, 4 mg/dl (<2 mg/dl); procalcitonine 0.3 ng/ml (<0.5 ng/ml)

Blood cultureNegative

Urine cultureNegative

Cerebrospinal fluid cultureNegative

Chest X-rayBilateral pulmonary infiltrates and significant cardiomegaly

EchocardiographyDiffuse pericardial effusion affecting predominantly right chambers. Ejection fraction: 76%; shortening fraction: 41%; LVO: 355 ml/kg/min; RVO: 395 ml/kg/min

PCR in nasopharyngeal swabPositive for parainfluenza 3 virus

Blood tests after the resolution of the pericardial effusionLeukocytes 9.8 cells/mm3(74.4% lymphocytes, 15% neutrophils); hemoglobin 13.1 g/dl and platelet count 255/mm3. ALT 89 U/L/AST 73 U/L, C-reactive protein (CRP) 1.7 mg/dl; procalcitonine 0.07 ng/ml