|
| Citation | Age/gender | Pathogen | Site | Reason for arthroplasty | Predisposing factors | Time to symptom onset | Surgical treatment | Medical treatment | Outcome |
|
| [5] | 67/F | MAC | Hip | DJD | Renal transplant on cyclosporine, prednisone | 15 yrs after arthroplasty
13 yrs after transplant | I&D, removal of prosthesis, spacer placement
Repeat I&D and spacer removal for sterile wound drainage 4 months post-op | Azithromycin, ethambutol, rifabutin | Planned reimplantation at 6 months and antimycobacterial coverage for total of 18 months |
|
| [6] | 41/M | MAI (disseminated) | Knee | Salmonella septic arthritis | Suspected underlying immunodeficiency syndrome
Polymyositis on prednisolone | 15 mo after TKR (MRSA isolated after TKR) | Repeat debridements | Multiple antibiotic regimens | Died due to sepsis with MRSA, E.coli, K.pneumoniae, MAI, Candida 7 months after initial MAI culture |
|
| [7] | NR | M. avium | Hip | Osteonecrosis | Heart transplant on cyclosporine, prednisone | NR | None | Ethambutol, rifampin, isoniazid | Doing well at time of follow-up (time NR) |
|
| [8] | 20/M | MAC (disseminated) | Bilateral hips | Perthes disease | AIDS | 20 yrs after arthroplasty
4 yrs after HIV diagnosis | Right hip resection arthroplasty | Ciprofloxacin, clarithromycin, rifampicin, clofazimine | Died 5 months post-op |
|
| [9] | 73/M | MAI (disseminated) | Knee | DJD | Multiple myeloma on lenalidomide, dexamethasone
RA on methotrexate
Previous pulmonary and olecranon MAC infections | 3 yr after chemotherapy,
1 yr after arthroplasty | Resection arthroplasty (reimplantation 7 mo post-op) | Clarithromycin, ethambutol | Doing well at 7 years of follow up |
|
| [10] | 39/M | MAI (disseminated) | Hip | Osteonecrosis | Renal transplant | NR | Resection arthroplasty | Azithromycin, ethambutol > 12 mo; did not tolerate rifabutin | No recurrence on ethambutol, clarithromycin; reimplantation of prosthesis not performed |
|
