Case Reports in Infectious Diseases
Volume 2017, Article ID 9028543, 5 pages
https://doi.org/10.1155/2017/9028543
Successful Treatment of Klebsiella pneumoniae Harboring a Klebsiella pneumoniae Carbapenemase Isolated from Lumbar Wound Infection and Blood in a Patient with Hardware Retention
1Division of Infectious Diseases and Antimicrobial Stewardship, St. Francis Hospital, Roslyn, NY, USA
2The Dr. James J. Rahal, Jr. Division of Infectious Diseases, Department of Medicine, NewYork-Presbyterian/Queens, Flushing, NY, USA
Correspondence should be addressed to Carl Urban; gro.pyn@nabrumc
Received 2 June 2017; Accepted 7 August 2017; Published 17 September 2017
Academic Editor: Gernot Walder
Copyright © 2017 Alan Bulbin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Infections caused by carbapenem-resistant Enterobacteriaceae, especially carbapenemase producing Klebsiella pneumoniae, represent an urgent threat as outlined by the Centers for Disease Control and Prevention (CDC). We present a 66-year-old male with spinal stenosis who underwent elective L2-pelvis posterior spinal fusion at an outside institution and rapidly developed a complicated infection with Klebsiella pneumoniae harboring Klebsiella pneumoniae carbapenemase. This is the first described case of a patient with Klebsiella pneumoniae harboring Klebsiella pneumoniae carbapenemase causing postoperative lumbar wound infection and bacteremia, successfully treated with ceftazidime-avibactam in combination with additional synergistic antibacterials and without hardware removal.