Infection of a Ventricular Septal Defect Patch with Acremonium Species

Table 2

Summary of case reports of Acremonium endocarditis.

Case reports	This case	Panzaru et al. [12]	Guarro et al. [9]	Heitmann et al. [3]	Lacaz Cda et al. [10]	Degeorges et al. [11]
Age/gender	21 years/male	51 years/male	73 years/male	80 years/male	47 years/male	31 years/male
Risk factors	TOF repair with Dacron Patch over VSD	Immunocompetent, admitted with pneumonia and CHF	Severe COPD on steroids, prosthetic mitral valve	Had been on steroids for inflammatory eye disease, pacemaker	Prosthetic valve	Aortic stenosis
Species isolated	Acremonium spp.	Acremonium spp.	Acremonium strictum	Acremonium spp.	Acremonium kiliense	Acremonium spp.
Valve involved	No valves, VSD patch only	Pulmonary and tricuspid valves	Prosthetic mitral valve	Pacemaker related tricuspid valve	Prosthetic mitral valve	Aortic valve
Treatment given	Amphotericin deoxycholate and voriconazole for 3 months then voriconazole for 12 months, removal of Dacron Patch	Fluconazole 400 mg twice daily for 30 days	Caspofungin followed by voriconazole	Voriconazole for 6 weeks	Amphotericin B, 5 flucytosine, surgery	Amphotericin B
Outcome	Recovered	Recovered	Died	Recovered	Died	Died