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Case Reports in Infectious Diseases
Volume 2019, Article ID 1613072, 3 pages
Case Report

Successful Management of Cryptococcal Meningitis and Bone Marrow Infiltration in a Young HIV/AIDS Patient: A Case Report and Review of the Literature

1University of Maryland Medical Center, Internal Medicine, 22 S Greene St., Baltimore, MD 21201, USA
2Tufts Medical Center, 800 Washington St., Boston, MA 02111, USA
3Tufts Medical Center, Hematology/Oncology, 800 Washington St., Boston, MA 02111, USA
4Tufts Medical Center, Infectious Disease, 800 Washington St., Boston, MA 02111, USA

Correspondence should be addressed to Sonika Patel; ude.dnalyramu.mos@letap.akinos

Received 20 November 2018; Accepted 21 January 2019; Published 19 February 2019

Academic Editor: Gloria Taliani

Copyright © 2019 Sonika Patel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Bone marrow cryptococcosis has been rarely reported in the literature, and there are no established treatment guidelines specific to this AIDS-related complication. The recommended treatment for AIDS-related invasive fungal treatments include amphotericin B and flucytosine which are associated with an array of complications making optimal treatment recommendations difficult. This case presentation represents an example of a patient with newly diagnosed AIDS and bone marrow cryptococcosis, which was successfully managed with an antifungal regimen adjusted to her comorbidities.