Case Reports in Infectious Diseases / 2019 / Article / Tab 1

Case Series

Anaerobic Bacteremias in Left Ventricular Assist Devices and Advanced Heart Failure

Table 1

Relevant clinical features of patients with anerobic bacteremias.

Clinical featurePatient 1Patient 2Patient 3Patient 4

ComorbiditiespHTN, OSA, IDA, obesityDilated cardiomyopathy, HTN, Afib, T2DM, goutNonischemic cardiomyopathyT2DM, current smoking
LVAD presentYesYesYesYes
Driveline culturesNoYes (previously)Yes (during second admission)Yes
LVAD-related infectionNoYes (history of)Yes (as a complication)Yes
Risk factorsDrug abuse, former smokerLiable INR, several GI bleedingAnticoagulationPoor dentition LVAD infection
Isolated bacteriaFusobacterium nucleatumBacteroides thetaiotaomicron/Citrobacter FreundiiFusobacterium nucleatumParvimonas micra
SourceLung (PNA)PNA vs. transient GI translocationPNAMouth
OutcomeImprovementSevere septic shockCardiogenic shock and coagulopathyLVAD thrombosis
Recurrent bacteremiaNoYesYesYes
GI bleedingNoYesNoNo
30 daysNoNoNoNo
90 daysNoNoYesNo
1 yearNoYesYesN/A
Cause of deathSeptic shock due to S. aureus bacteremiaSeptic shock due to Citrobacter freundiiLVAD thrombosis, Rhizopus pocket infection, and hemorrhagic strokeN/A

Afib: atrial fibrillation, GI: gastrointestinal, HTN: hypertension, IDA: iron deficiency anemia, LVAD: left ventricular assisted device; MTZ: metronidazole, OSA: obstructive sleep apnea, pHTN: pulmonary hypertension, PNA: pneumonia, T2DM: type 2 diabetes mellitus.

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