Presentation of Ocular Syphilis in a HIV-Positive Patient with False-Negative Serologic Screening

Table 1

Serologic screening results. Upon initial presentation, the traditional testing algorithm was utilized. However, at the time of follow-up (secondary results), the alternative testing algorithm was followed.

Serologic test	Initial test results	Secondary test results (48 hours later)	Reference ranges
RPR screen	Nonreactive	Reactive	Nonreactive
RPR titer	Nonreactive	1 : 512	Nonreactive
Syphilis antibody total	N/A	6.8	≤0.8
Syphilis antibody result	N/A	Reactive	Nonreactive
Treponema pallidum antibody	N/A	Reactive	Nonreactive

RPR, rapid plasma reagin.