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Citation | Patient details | Initial symptoms | Time from initial symptoms to ocular symptoms (weeks) | Ocular symptoms | Ocular signs | Antibody to B. burgdorferi | Antibody to B. burgdorferi | Opening pressure (cm H2O) | CSF white cells | Brain MRI findings | Treatment | Outcome |
Bands on WB | CSF/serum ratio |
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Rothermel et al. [11] | An 8-year-old male | Headache | 8 | Decreased vision | Swollen discs with elevation of the retina | 10/10 IgG bands | Not done | Normal | 0 | Normal | Ceftriaxone | Resolution of symptoms |
A 16-year-old male | Knee arthritis | 28 | Blurred vision of the left eye | Swollen optic disc, central scotoma | 8/10 IgG bands | Not done | Normal | <10 | Normal | Ceftriaxone | Resolution of symptoms |
A 13-year-old girl | Fever, headache, and neck pain | 3 | Horizontal diplopia and eye pain | Bilateral papilledema, sixth nerve palsy, and decreased visual acuity | 7/10 IgG bands | IgG 1.42 | 60 | 82 | Normal | Ceftriaxone | Resolution of symptoms |
An 11-year-old male | Rash, headaches, vomiting, and fever | 2.5 | Double vision | Photophobia and bilateral sixth and seventh nerve palsies | 8/10 IgG bands | <1 for IgG, IgM, and IgA | 57 | 3 | — | Ceftriaxone and methylprednisolone | Improvement in symptoms with residual sixth nerve palsy |
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Ezequiel et al. [7] | A 9-year-old male | Headache, pallor, photophobia, and phonophobia | — | — | Papilledema | Positive | Positive IgG and IgM | 50 | 30 | Normal | Ceftriaxone | Resolution of symptoms |
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Kan et al. [4] | An 8-year-old female | Headaches, vomiting, and diplopia | — | Diplopia | Papilledema and left sixth nerve palsy | Positive | Positive CSF antibodies | 32 | 115 | Dural enhancement | Ceftriaxone and acetazolamide | Papilledema resolved, and mild sixth nerve palsy remained |
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