Case Series

Ceftriaxone as an Alternative Therapy for the Treatment of Methicillin-Susceptible Staphylococcus aureus Bacteremia after Initial Clearance of Bloodstream Infection

Table 3

Clinical outcomes.

Variable presented as #(%) or median (IQR)Ceftriaxone (n = 20)SOCT alone (n = 23) value

Clinical cure10 (50)18 (78.3)0.052
 WBC normal in 7 days12 (60)20 (87)0.043
 Temp normal in 7 days20 (100)23 (100)1.000
 Culture clear in 7 days16 (80)18 (78.3)1.000
Microbiological cure16 (80)21 (91.3)0.393
Recurrence within 60 days2 (10)3 (13)1.000
Hospital length of stay16.5 [9–22.75]12 [8–26]0.669
MSSA length of stay16 [8.25–22.75]11 [8–19]0.479
Discharge disposition
 Death1 (5)1 (4.3)1.000
 Home13 (65)16 (69.6)0.750
 SNF/Rehab6 (30)6 (26.1)0.775
Alive, not readmitted or retreated16 (80)17 (73.9)0.728
Infection-related readmission2 (10)4 (17.4)0.669
Not infection-related readmission2 (10)1 (4.3)0.590

WBC = white blood cell; MSSA = methicillin-susceptible Staphylococcus aureus; SNF = skilled nursing facility; Rehab = rehabilitation facility.