TY - JOUR
A2 - Firstenberg, Michael S.
AU - Antonuzzo, L.
AU - Rotella, V.
AU - Mazzoni, F.
AU - Doni, L.
AU - Bianchini, D.
AU - Garbini, F.
AU - Maio, V.
AU - Di Costanzo, F.
PY - 2009
DA - 2009/08/20
TI - Primary Cardiac Angiosarcoma: A Fatal Disease
SP - 591512
VL - 2009
AB - A 42-year-old man with a cardiac tamponade underwent an urgent pericardiotomy that showed tumoral tissue, covering the surface of the right atrium. The tumor was then partially excised, and the histological examination revealed the presence of a moderately-differentiated angiosarcoma. The patient was then referred to the oncology unit and scheduled for a chemotherapy schedule including Epirubicin (60 mg/m2, on days 1 and 2) plus Ifosfamide (2000 mg/m2, on days 1 to 3) and Uromitexan (2000 mg/m2 at hours 0, 4, 8 after IFO). All drugs were administered every three weeks. After two cycles, a restaging work-up revealed a partial remission. The treatment was continued for another two cycles. A new evaluation by cardiac MRI evidenced a local and distant (lung) progression of disease. The patient died after three months. This paper confirms that cardiac angiosarcoma is a fatal disease, and the prognosis is usually 6–11 months from time of diagnosis.
SN - 1687-9627
UR - https://doi.org/10.1155/2009/591512
DO - 10.1155/2009/591512
JF - Case Reports in Medicine
PB - Hindawi Publishing Corporation
KW -
ER -