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Case Reports in Medicine
Volume 2009, Article ID 705635, 4 pages
http://dx.doi.org/10.1155/2009/705635
Case Report

A Seizure Attributed to Ofloxacine in a Woman Undergoing Detoxification for Alcohol Dependence

Centre de Traitement des Addictions, Hôpital Emile Roux, Assistance Publique-Hôpitaux de Paris, 94450 Limeil-Brévannes, France

Received 13 October 2009; Accepted 2 December 2009

Academic Editor: Paul Dargan

Copyright © 2009 Pierre Lahmek et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. A. O'Donnell and S. P. Gelone, “Fluoroquinolones,” Infectious Disease Clinics of North America, vol. 14, no. 2, pp. 489–513, 2000. View at Google Scholar
  2. J. M. Kushner, H. J. Peckman, and C. R. Snyder, “Seizures associated with fluoroquinolones,” Annals of Pharmacotherapy, vol. 35, no. 10, pp. 1194–1198, 2001. View at Google Scholar
  3. M. A. Schuckit, “Alcohol-use disorders,” The Lancet, vol. 373, no. 9662, pp. 492–501, 2009. View at Publisher · View at Google Scholar
  4. J. R. Hughes, “Alcohol withdrawal seizures,” Epilepsy and Behavior, vol. 15, no. 2, pp. 92–97, 2009. View at Publisher · View at Google Scholar · View at PubMed
  5. J. F. Annegers, S. Dubinsky, S. P. Coan, M. E. Newmark, and L. Roht, “The incidence of epilepsy and unprovoked seizures in multiethnic, urban health maintenance organizations,” Epilepsia, vol. 40, no. 4, pp. 502–506, 1999. View at Google Scholar
  6. J. F. Annegers, W. A. Hauser, J. R.-J. Lee, and W. A. Rocca, “Incidence of acute symptomatic seizures in Rochester, Minnesota, 1935–1984,” Epilepsia, vol. 36, no. 4, pp. 327–333, 1995. View at Publisher · View at Google Scholar
  7. “In the clinic. Alcohol use,” Annals of Internal Medicine, vol. 150, no. 5, pp. ITC3-1–ITC3-15, 2009.
  8. M. F. Mayo-Smith, “Pharmacological management of alcohol withdrawal: a meta-analysis and evidence-based practice guideline,” Journal of the American Medical Association, vol. 278, no. 2, pp. 144–151, 1997. View at Google Scholar
  9. J. A. French and T. A. Pedley, “Clinical practice. Initial management of epilepsy,” The New England Journal of Medicine, vol. 359, no. 2, pp. 166–176, 2008. View at Publisher · View at Google Scholar · View at PubMed
  10. C. L. Harden, J. S. Huff, T. H. Schwartz et al., “Reassessment: neuroimaging in the emergency patient presenting with seizure (an evidence-based review): report of the therapeutics and technology assessment subcommittee of the American Academy of Neurology,” Neurology, vol. 69, no. 18, pp. 1772–1780, 2007. View at Publisher · View at Google Scholar · View at PubMed
  11. A. Krumholz, S. Wiebe, G. Gronseth et al., “Practice parameter: evaluating an apparent unprovoked first seizure in adults (an evidence-based review): report of the quality standards subcommittee of the American Academy of Neurology and the American Epilepsy Society,” Neurology, vol. 69, no. 21, pp. 1996–2007, 2007. View at Publisher · View at Google Scholar · View at PubMed
  12. A. T. Berg, “Risk of recurrence after a first unprovoked seizure,” Epilepsia, vol. 49, supplement 1, pp. 13–18, 2008. View at Publisher · View at Google Scholar · View at PubMed
  13. J. H. Krystal, J. Staley, G. Mason et al., “γ-aminobutyric acid type A receptors and alcoholismml: intoxication, dependence, vulnerability, and treatment,” Archives of General Psychiatry, vol. 63, no. 9, pp. 957–968, 2006. View at Publisher · View at Google Scholar · View at PubMed
  14. J. T. Sullivan, K. Sykora, J. Schneiderman, C. A. Naranjo, and E. M. Sellers, “Assessment of alcohol withdrawal: the revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar),” British Journal of Addiction, vol. 84, no. 11, pp. 1353–1357, 1989. View at Google Scholar
  15. C. Sannibale, L. Fucito, D. O'Connor, and K. Curry, “Process evaluation of an out-patient detoxification service,” Drug and Alcohol Review, vol. 24, no. 6, pp. 475–481, 2005. View at Publisher · View at Google Scholar · View at PubMed
  16. C. A. Naranjo, U. Busto, E. M. Sellers et al., “A method for estimating the probability of adverse drug reactions,” Clinical Pharmacology and Therapeutics, vol. 30, no. 2, pp. 239–245, 1981. View at Google Scholar
  17. A. J. Mehlhorn and D. A. Brown, “Safety concerns with fluoroquinolones,” Annals of Pharmacotherapy, vol. 41, no. 11, pp. 1859–1866, 2007. View at Publisher · View at Google Scholar · View at PubMed
  18. W. Christ, “Central nervous system toxicity of quinolones: human and animal findings,” Journal of Antimicrobial Chemotherapy, vol. 26, supplement B, pp. 219–225, 1990. View at Google Scholar
  19. A. De Sarro and G. De Sarro, “Adverse reactions to fluoroquinolones. An overview on mechanistic aspects,” Current Medicinal Chemistry, vol. 8, no. 4, pp. 371–384, 2001. View at Google Scholar
  20. K. Akahane, M. Kato, and S. Takayama, “Involvement of inhibitory and excitatory neurotransmitters in levofloxacin- and ciprofloxacin-induced convulsions in mice,” Antimicrobial Agents and Chemotherapy, vol. 37, no. 9, pp. 1764–1770, 1993. View at Google Scholar
  21. T. Darwish, “Ciprofloxacin-induced seizures in a healthy patient,” New Zealand Medical Journal, vol. 121, no. 1277, pp. 104–105, 2008. View at Google Scholar
  22. M. T. Schwartz and J. F. Calvert, “Potential neurologic toxicity related to ciprofloxacin,” DICP, The Annals of Pharmacotherapy, vol. 24, no. 2, pp. 138–140, 1990. View at Google Scholar
  23. P. Tattevin, T. Messiaen, V. Pras, P. Ronco, and M. Biour, “Confusion and general seizures following ciprofloxacin administration,” Nephrology Dialysis Transplantation, vol. 13, no. 10, pp. 2712–2713, 1998. View at Publisher · View at Google Scholar
  24. G. D. Anastasio, D. Menscer, and J. M. Little Jr., “Norfloxacin and seizures,” Annals of Internal Medicine, vol. 109, no. 2, pp. 169–170, 1988. View at Google Scholar
  25. S. B. Bird, P. G. Orr, J. L. Mazzola, D. E. Brush, and E. W. Boyer, “Levofloxacin-related seizure activity in a patient with Alzheimer's disease: assessment of potential risk factors,” Journal of Clinical Psychopharmacology, vol. 25, no. 3, pp. 287–288, 2005. View at Publisher · View at Google Scholar
  26. M. J. Christie, K. Wong, R. H. Ting, P. Y. Tam, and T. G. Sikaneta, “Generalized seizure and toxic epidermal necrolysis following levofloxacin exposure,” Annals of Pharmacotherapy, vol. 39, no. 5, pp. 953–955, 2005. View at Publisher · View at Google Scholar · View at PubMed
  27. S. Melvani and B. R. Speed, “Alatrofloxacin-induced seizures during slow intravenous infusion,” Annals of Pharmacotherapy, vol. 34, no. 9, pp. 1017–1019, 2000. View at Google Scholar
  28. C. A. Quigley and J. R. Lederman, “Possible gatifloxacin-induced seizure,” Annals of Pharmacotherapy, vol. 38, no. 2, pp. 235–237, 2004. View at Publisher · View at Google Scholar · View at PubMed
  29. S. Sire, T. Staub-Schmidt, J. M. Ragnaud, D. Christmann, and J. Aubertin, “Convulsion induced by ofloxacin,” Revue de Medecine Interne, vol. 17, no. 7, pp. 601–602, 1996. View at Publisher · View at Google Scholar
  30. S. M. Traeger, M. F. Bonfiglio, J. A. Wilson, B. R. Martin, and N. A. Nackes, “Seizures associated with ofloxacin therapy,” Clinical Infectious Diseases, vol. 21, no. 6, pp. 1504–1506, 1995. View at Google Scholar
  31. G. D. Walton, J. K. Hon, and T. G. Mulpur, “Ofloxacin-induced seizure,” Annals of Pharmacotherapy, vol. 31, no. 12, pp. 1475–1477, 1997. View at Google Scholar
  32. H. Yasuda, A. Yoshida, Y. Masuda, M. Fukayama, Y. Kita, and T. Inamatsu, “Levofloxacin-induced neurological adverse effects such as convulsion, involuntary movement (tremor, myoclonus and chorea like), visual hallucination in two elderly patients,” Nippon Ronen Igakkai Zasshi, vol. 36, no. 3, pp. 213–217, 1999. View at Google Scholar
  33. K. J. Simpson and M. J. Brodie, “Convulsions related to enoxacin,” The Lancet, vol. 2, no. 8447, p. 161, 1985. View at Google Scholar
  34. A. G. Fraser and A. D. B. Harrower, “Convulsions and hyperglycaemia associated with nalidixic acid,” British Medical Journal, vol. 2, no. 6101, p. 1518, 1977. View at Google Scholar
  35. M. Jo, N. Tachi, and M. Shinoda, “Convulsions from excessive dosage of nalidixic acid: a case report,” Brain and Development, vol. 1, no. 4, pp. 327–329, 1979. View at Google Scholar
  36. E. Rubinstein, “History of quinolones and their side effects,” Chemotherapy, vol. 47, supplement 3, pp. 3–8, 2001. View at Google Scholar
  37. G. Schmuck, A. Schurmann, and G. Schluter, “Determination of the excitatory potencies of fluoroquinolones in the central nervous system by an in vitro model,” Antimicrobial Agents and Chemotherapy, vol. 42, no. 7, pp. 1831–1836, 1998. View at Google Scholar
  38. P. D. Williams and D. R. Helton, “The proconvulsive activity of quinolone antibiotics in an animal model,” Toxicology Letters, vol. 58, no. 1, pp. 23–28, 1991. View at Google Scholar
  39. N. Akaike, T. Shirasaki, and T. Yakushiji, “Quinolones and fenbufen interact with GABA(A) receptor in dissociated hippocampal cells of rat,” Journal of Neurophysiology, vol. 66, no. 2, pp. 497–504, 1991. View at Google Scholar
  40. C. Brochot, S. Marchand, W. Couet, A. Gelman, and F. Y. Bois, “Extension of the isobolographic approach to interactions studies between more than two drugs: illustration with the convulsant interaction between pefloxacin, norfloxacin, and theophylline in rats,” Journal of Pharmaceutical Sciences, vol. 93, no. 3, pp. 553–562, 2004. View at Publisher · View at Google Scholar · View at PubMed
  41. T. Yoshino, M. Noguchi, H. Okutsu, A. Kimoto, M. Sasamata, and K. Miyata, “Celecoxib does not induce convulsions nor does it affect GABAA receptor binding activity in the presence of new quinolones in mice,” European Journal of Pharmacology, vol. 507, no. 1–3, pp. 69–76, 2005. View at Publisher · View at Google Scholar · View at PubMed
  42. T. E. Poe, G. S. Marion, and D. S. Jackson, “Seizures due to nalidixic acid therapy,” Southern Medical Journal, vol. 77, no. 4, pp. 539–540, 1984. View at Google Scholar