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Case Reports in Medicine
Volume 2010, Article ID 135029, 4 pages
http://dx.doi.org/10.1155/2010/135029
Case Report

Testicular Hamartomas and Epididymal Tumor in a Cowden Disease: A Case Report

Departments of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, The Chinese University of Hong Kong, Ngan Shing Street, Shatin, New Territories, Hong Kong

Received 19 December 2009; Accepted 8 May 2010

Academic Editor: Simon Ching-Shun Kao

Copyright © 2010 Darshana D. Rasalkar and Bhawan K. Paunipagar. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. K. M. Lloyd and M. Dennis, “Cowden's disease. A possible new symptom complex with multiple system involvement,” Annals of Internal Medicine, vol. 58, pp. 136–142, 1963. View at Google Scholar
  2. P. E. Weary, R. J. Gorlin, W. C. Gentry Jr., J. E. Comer, and K. E. Greer, “Multiple hamartoma syndrome (Cowden's disease),” Archives of Dermatology, vol. 106, no. 5, pp. 682–690, 1972. View at Publisher · View at Google Scholar · View at Scopus
  3. M. R. Nelen, H. Kremer, and H. Kremer, “Novel PTEN mutations in patients with Cowden disease: absence of clear genotype-phenotype correlations,” European Journal of Human Genetics, vol. 7, no. 3, pp. 267–273, 1999. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  4. M. Botma, D. I. Russell, and R. A. Kell, “Cowden's disease: a rare cause of oral papillomatosis,” Journal of Laryngology and Otology, vol. 116, no. 3, pp. 221–223, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. J. A. Hobert and C. Eng, “PTEN hamartoma tumor syndrome: an overview,” Genetics in Medicine, vol. 11, no. 10, pp. 687–694, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  6. C. Eng, “Will the real Cowden syndrome please stand up: revised diagnostic criteria,” Journal of Medical Genetics, vol. 37, no. 11, pp. 828–830, 2000. View at Google Scholar · View at Scopus
  7. C. Lindsay, L. Boardman, and M. Farrell, “Testicular hamartomas in Cowden disease,” Journal of Clinical Ultrasound, vol. 31, no. 9, pp. 481–483, 2003. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  8. J. Woodhouse and M. M. Ferguson, “Multiple hyperechoic testicular lesions are a common finding on ultrasound in Cowden disease and represent lipomatosis of the testis,” British Journal of Radiology, vol. 79, no. 946, pp. 801–803, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  9. B. Hamm, “Differential diagnosis of scrotal masses by ultrasound,” European Radiology, vol. 7, no. 5, pp. 668–679, 1997. View at Google Scholar · View at Scopus
  10. D. C. Howlett, N. D. P. Marchbank, and D. F. Sallomi, “Ultrasound of the testis,” Clinical Radiology, vol. 55, no. 8, pp. 595–601, 2000. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  11. M. T. Kuhn and G. T. MacLennan, “Benign neoplasms of the epididymis,” Journal of Urology, vol. 174, no. 2, p. 723, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. J. R. Srigley and R. W. Hartwick, “Tumors and cysts of the paratesticular region,” Pathology Annual, vol. 25, pp. 51–108, 1990. View at Google Scholar · View at Scopus
  13. W. G. Alleman, B. Gorman, B. F. King, D. R. Larson, J. C. Cheville, and A. Nehra, “Benign and malignant epididymal masses evaluated with scrotal sonography. Clinical and pathologic review of 85 patients,” Journal of Ultrasound in Medicine, vol. 27, no. 8, pp. 1195–1202, 2008. View at Google Scholar · View at Scopus
  14. T. M. Ulbright, M. B. Amin, and R. H. Young, “Miscellaneous primary tumors of the testis, adnexa, and spermatic cord,” in Atlas of Tumor Pathology, fasc 25, J. Rosai and L. H. Sobin, Eds., 3, pp. 235–366, Armed Forces Institute of Pathology, Washington, DC, USA, 1999. View at Google Scholar
  15. D. G. Bostwick, “Spermatic cord and testicular adnexa,” in Urologic Surgical Pathology, D. G. Bostwick and J. N. Eble, Eds., pp. 647–674, Mosby, St Louis, Mo, USA, 1997. View at Google Scholar