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Case Reports in Medicine
Volume 2010, Article ID 313514, 3 pages
http://dx.doi.org/10.1155/2010/313514
Case Report

Unusual Methylobacterium fujisawaense Infection in a Patient with Acute Leukaemia Undergoing Hematopoietic Stem Cell Transplantation: First Case Report

1Haematology Unit, Department of Critical Care Medicine and Surgery, Careggi Hospital, University of Florence, School of Medicine, 50134 Florence, Italy
2Infectious Disease Unit, Department of Critical Care Medicine and Surgery, Careggi Hospital, University of Florence, School of Medicine, 50134 Florence, Italy
3Microbiology Laboratory, Azienda Ospedaliero-Universitaria Careggi, Careggi Hospital, Florence, Italy
4Genetics and Citogenetics Unit, Azienda Ospedaliero-Universitaria Careggi, Careggi Hospital, Florence, Italy

Received 11 December 2009; Revised 16 March 2010; Accepted 22 March 2010

Academic Editor: Jacques F. Meis

Copyright © 2010 Rosa Fanci et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Microorganisms of the genus Methylobacterium are facultative methylotrophic, gram-negative rods that are ubiquitous in nature and rarely cause human disease, mostly in subjects with preexisting causes of immune depression. Methylobacterium fujisawaense, first proposed as a new species in 1988, has never been reported as a bacterial agent of human infections so far. Here we describe a case of M. fujisawaense infection in a relapsed acute leukaemia undergoing unrelated allogeneic hematopoietic stem cell transplantation. Molecular identification of an M. fujisawaense strain was obtained from multiple mycobacterial blood cultures.