Case Report

Successful Control of Acute Myelofibrosis with Lenalidomide

Table 1

The basic characteristics that help in the differential diagnosis of APMF (acute panmyelosis with myelofibrosis), PMF (primary myelofibrosis), and the 5q-syndrome according to the recent WHO classification (2008).

APMFPMF5q-

MGK increaseProminentPresentPresent
JAK2V617FNoYes (50%)No
Acute onsetYesNoNo
SplenomegalyNoYesNo
Marrow FibrosisYesYesNo
PancytopeniaYesNoNo