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Case Reports in Medicine
Volume 2010, Article ID 487579, 4 pages
Case Report

Tako-Tsubo Cardiomyopathy in a Patient with Advanced Colorectal Adenocarcinoma

Department of Internal Medicine, Marshfield Clinic, Marshfield, WI 54449, USA

Received 16 November 2009; Revised 3 February 2010; Accepted 21 March 2010

Academic Editor: Grigorios Korosoglou

Copyright © 2010 Yusuf Kasirye and Ihab B. Abdalrahman. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Transient left ventricular dysfunction syndrome (TLVDS), or Tako-Tsubo cardiomyopathy (TC), is a clinical entity in which patients present with features of acute coronary syndrome, electrocardiogram abnormalities, and transient left ventricular (apical or mid-ventricular) dysfunction. Patients usually recover from this condition four to six weeks after the event. The etiology or triggering factors of TC remains unknown. Various triggering factors have been associated with this syndrome, with one of the most recent being malignancies. In this case report we present a postmenopausal female with underlying advanced malignancy who presented with TC. This is consistent with a recent hypothesis that in addition to currently known triggering factors, malignancies might well trigger TC in the context of a stressor or paraneoplastic phenomenon.