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Case Reports in Medicine
Volume 2010, Article ID 634975, 3 pages
Case Report

Bone Metastasis as the Only Metastatic Site in a Patient with Pancreatic Cancer following Distal Pancreatectomy

1Division of Hematology/Oncology, Department of Medicine, Columbia University College of Physicians and Surgeons, NY 10032, USA
2GI Oncology Section, Division of Hematology/Oncology, Herbert Irving Comprehensive Cancer Center (HICCC), Columbia University, NY 10032, USA
3Pancreas Center, New York Presbyterian Hospital, NY 10032, USA
4School of Medicine, Yale University, New Haven, CT 06510, USA

Received 5 May 2010; Accepted 26 July 2010

Academic Editor: Lothar Bergmann

Copyright © 2010 Muhammad Wasif Saif et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Pancreatic cancer remains a challenge both diagnostically and therapeutically. The typical sites of metastases in pancreatic cancer include the liver and peritoneum. Other less common sites are the lung, brain, kidney, and bone. Skeletal metastases are less prevalent in occurrence but contribute to significant morbidity associated with pancreatic cancer. The prevalence of osseous metastases remains unknown but has been estimated to be between 5% and 20%. The most common osseous lesions are osteolytic in nature, but the osteoblastic ones are extremely rare. Here, we report an interesting case of pancreatic adenocarcinoma with exclusive bone metastases and discuss briefly the possible pathogenesis.