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Case Reports in Medicine
Volume 2010, Article ID 682081, 4 pages
Case Report

Adrenocortical Secreting Mass in a Patient with Gardner's Syndrome: A Case Report

Department of Diabetes and Endocrinology, Hedi Chaker Hospital, Magida Boulila Avenue. Sfax 3029, Tunisia

Received 16 August 2010; Accepted 15 November 2010

Academic Editor: Christian C. Apfel

Copyright © 2010 Nabila Mejdoub Rekik et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Gardner's syndrome (GS) is a dysplasia characterized by neoformations of the intestine, soft tissue, and osseous tissue. Endocrine neoplasms have occasionally been reported in association with GS. Adrenal masses in GS are rare, and few have displayed clinical manifestations. In the current paper, The authors report a 37-year-old male patient with GS including familial adenomatous polyposis (FAP) and mandible osteoma who presented with an incidental adrenal mass. Computerized tomography adrenal scan identified bilateral masses. Functional analyses showed a hormonal secretion pattern consistent with pre-Cushing's syndrome. Other extraintestinal manifestations were hypertrophy of the pigmented layer of the retina and histiocytofibroma in the right leg. This paper describes a rare association of adrenocortical secreting mass in an old male patient with Gardner syndrome.