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Case Reports in Medicine
Volume 2010, Article ID 820506, 3 pages
http://dx.doi.org/10.1155/2010/820506
Case Report

Acute Hepatitis B and Acute HIV Coinfection in an Adult Patient: A Rare Case Report

1Department of Medicine, Mount Sinai Elmhurst Hospital Center, 7901 Broadway, Elmhurst, NY 11373, USA
2Division of Infectious Diseases, Mount Sinai Elmhurst Hospital Center, 7901 Broadway, Elmhurst, NY 11373, USA
3Department of Gastroenterology, Mount Sinai Elmhurst Hospital Center, 7901 Broadway, Elmhurst, NY 11373, USA

Received 21 May 2010; Accepted 14 September 2010

Academic Editor: Andreas G. Tzakis

Copyright © 2010 Raghav Bansal et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Acute HIV and acute hepatitis B coinfection is extremely rare. A 23-year-old homosexual man was admitted to our hospital with 5-day history of fever, malaise, and back pain with initial laboratory values showing severe transaminitis. The clinical picture was initially suggestive of acute viral hepatitis, which on further testing revealed acute hepatitis B and acute HIV coinfection. Although the patient was asymptomatic, a decision was made to start antiretroviral therapy. At 2-month followup, liver function tests were normal with undetectable viral loads. The early treatment of acute HIV/HBV coinfections likely contributed to eventual seroconversion with immunity to HBV in a severely immunocompromised host. To the best of our knowledge, this is the first case report of acute Hepatitis B and acute HIV coinfection and its management. In conclusion, early treatment of acute hepatitis B in immunocompromised patients may be beneficial.