Malignant Hyperthermia and Idiopathic HyperCKemia

Table 1

Summary of 2 studies specifically studying the susceptibility of developing MH in patients with unexplained hyperCKemia.

Study	Sample size	Testing	Outcome
(1) Malandrini et al. [3]	37; (i) 51.1% were asymptomatic; (ii) 26 males and 11 females	In vitro contracture testing with halothane-caffeine	1 MH susceptible (2.7%) and 1 MH equivocal patient; No familial cases noted in this study
(2) Weglinski et al. [2]	49; (i) All were asymptomatic; (ii) 36 males and 13 females	In vitro contracture testing with halothane-caffeine	24 (49%) had positive contracture tests; 14 patients had a family history of high CK levels