Thrombotic Thrombocytopenic Purpura Associated with Mixed Connective Tissue Disease: A Case Report

Table 1

Laboratory data.

	On admission	After 20 days	After 40 days
Complete blood count
RBC (×10^12/L)	2.88	3.97	4.55
Hemoglobin (g/dL)	7.8	11.5	12.4
Hematocrit (%)	23.8	35	39.6
MCV (fL)	82.6	88	87
MCH (pg)	27	29	27
MCHC (g/dL)	32.7	33	31
RDW (%)	21.2	17.6	13.2
WBC (×10^9/L)	9.8	5.72	7.23
Platelet (×10^9/L)	5.1	243	312
Reticulocytes (%)	8.4	1.1	0.8
Blood chemistry
AST (IU/L)	46	22	21
ALT (IU/L)	43	29.2	31
GGT (IU/L)	98	230	80
ALP (IU/L)	98	130	72
LDH (IU/L)	1830	365	176
Total bilirubin (mg/dL)	4.1	0.5	0.6
Direct bilirubin (mg/dL)	2.1	0.23	0.28
Indirect bilirubin (mg/dL)	2	0.27	0.32
Glucose (mg/dL)	128	98	89
Urea (mg/dL)	19
Creatinine (mg/dL)	0.6
Uric acid (mg/dL)	3.0
Sodium (mEq/L)	139
Potassium (mEq/L)	2.9
Hormones
TSH (μU/mL)	2.72
Free T4 (pg/dL)	1.08
Serology
HBsAg	Negative
Anti-HBs	Negative
Anti-HBc	Negative
Anti-HCV	Negative
Anti-HIV	Negative
Blood culture	Negative
Other blood tests
ESR (mm/hr)	78
PT (s)	10.2
aPTT (s)	21.3
Direct Coobs test	Negative
Urinalysis
Protein	(3+)
Leukocyte	(2+)
Hemoglobin	(4+)
Bilirubin	(1+)
Urobilinogen	(2+)
Nitrite	(—)
Urine culture	negative

RBC: red blood cells, MCV: mean corpuscular volume, MCH: mean corpuscular hemoglobin, MCHC: mean corpuscular hemoglobin concentration, RDW: red blood cell distribution width, WBC: white blood cells, AST: aspartate aminotransferase, ALT: alanine aminotransferase, ALP: alkaline phosphatase, GGT: gamaglutamil transferase, LDH: lactate dehydrogenase, ESR: erythrocyte sedimentation rate, PT: prothrombin time, ATTP: activated partial thromboplastin time, TSH: Thyroid-stimulating hormone.