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Case Reports in Medicine
Volume 2012, Article ID 168785, 5 pages
Case Report

Recurrent Plasmacytomas after Allografting in a Patient with Multiple Myeloma

1Department of Hematology and Oncology, Webber Cancer Center, St. John Macomb-Oakland Hospital, Warren, MI 48093, USA
2Department of Clinical Pathology, St. John Macomb-Oakland Hospital, Warren, MI 48093, USA
3Division of Hematology, University of Torino, Via Genova 3, 10126 Torino, Italy

Received 6 September 2012; Revised 25 November 2012; Accepted 12 December 2012

Academic Editor: Graham F. Pineo

Copyright © 2012 Allen N. Stawis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Extramedullary recurrence in multiple myeloma patients has been reported after both autologous and allogeneic hematopoietic cell transplantation and, more recently, after treatment with so-called new drugs with potent antimyeloma activity. Only a very few sizable reports focused on its clinical presentation and its incidence, which may be highly underestimated, and most observations are based on single patients reported from several institutions. Given the unusual sites of recurrence, diagnosis may be rather difficult and delayed treatment may play a relevant role in prognosis. Here we report a case of a myeloma patient, initially treated with an allograft, who enjoyed an eleven-year disease-free remission with very good quality of life. She eventually relapsed first with an extramedullary plasmacytoma in the breast and, two years later, with a right atrial cardiac mass.