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Case Reports in Medicine
Volume 2012 (2012), Article ID 253492, 2 pages
Case Report

A Successful Collagenase and Hyaluronic Acid Topical Use Combined with Antibiotic Therapy in the Treatment of Ulcerative Lesions Arising on Tattoo

Department of Plastic, Reconstructive and Aesthetic Surgery, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 155, 00161 Rome, Italy

Received 16 July 2012; Revised 17 September 2012; Accepted 26 September 2012

Academic Editor: J. W. M. Van der Meer

Copyright © 2012 Paolo Fioramonti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Tattooing is an ancient art widely practiced allover the world. The procedure used in making a tattoo consists of puncturing the dermis and depositing an amount of ink, but this decorative technique is not devoid of potential adverse effects, such as infectious complications, hypersensitivity reactions to pigments (lichenoid and granulomatous reactions), the development of benign or malignant tumors, and chronic dermatoses on site of the tattoo. We report an unusual complication which arose on a colorful tattoo and the innovative use of collagenase (Bionect Start) to treat it. With conservative treatment and the use of Bionect Start, we obtained complete resolution and reepithelialization of the lesions, in addition to perfect preservation of the colors of the tattoo.