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Case Reports in Medicine
Volume 2012, Article ID 405917, 4 pages
Case Report

Brain Metastasis of Nasopharyngeal Carcinoma: A Case Report and Literature Review

Oncology Institute, Rambam Health Care Campus, P.O. Box 9602, Haifa 31096, Israel

Received 11 October 2011; Revised 4 December 2011; Accepted 19 December 2011

Academic Editor: David W. Eisele

Copyright © 2012 Orit Kaidar-Person et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Central nervous system metastases from nasopharyngeal carcinoma (NPC) are uncommon. The patient presented was diagnosed with aggressive advanced NPC resistant to treatment and complicated by a solitary brain metastasis. A PubMed database search was conducted to review the existing literature regarding brain metastases of NPC, using the search terms “nasopharyngeal neoplasia,” “nasopharyngeal carcinoma,” “nasopharynx,” “radiotherapy,” “central nervous system,” and “brain” in section of “Title/Abstract.” The articles were first evaluated by title and then by abstract, and thereafter appropriate manuscripts were evaluated by full text. References of the published papers were also reviewed.