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Case Reports in Medicine
Volume 2012 (2012), Article ID 497362, 3 pages
Case Report

Malignant Transformation of Endometrioma in a Woman with a History of Ovulation Induction and In Vitro Fertilization

1School of Medicine, Wayne State University, 60 West Hancock Street, Detroit, MI 48201, USA
2Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, School of Medicine, Wayne State University, 60 West Hancock Street, Detroit, MI 48201, USA

Received 18 August 2012; Revised 31 October 2012; Accepted 1 November 2012

Academic Editor: Michail Varras

Copyright © 2012 Terri L. Woodard et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Our aim is to document a case of endometrioid adenocarcinoma of the ovary found in an endometriotic cyst that was suspected on pelvic ultrasound in a patient with polycystic ovary syndrome, normal Ca125, and a recent history of ovulation induction for IVF. She underwent an exploratory laparotomy with left salpingo-oophorectomy and omental biopsies followed by reexploration, complete staging, and modified radical abdominal hysterectomy and right salpingo-oophorectomy. An endometrioma described as suspicious for malignancy by an experienced ultrasound examiner should prompt immediate referral to a gynecological oncologist irrespective of Ca125 levels especially in women with a history of ovulation induction and endometriosis.