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Case Reports in Medicine
Volume 2012, Article ID 582607, 5 pages
http://dx.doi.org/10.1155/2012/582607
Case Report

Primary Follicular Lymphoma of the Duodenum with Erosions as Atypical Macroscopic Features

1Department of Gastroenterology, Mitoyo General Hospital, Kan'onji 769-1695, Japan
2Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan
3Department of Transfusion Medicine, Faculty of Medicine, Kagawa University, Kita-Gun 761-0793, Japan
4Department of Pathology, Mitoyo General Hospital, Kan'onji 769-1695, Japan
5Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan
6Department of Endoscopy, Okayama University Hospital, Okayama 700-8558, Japan

Received 16 February 2012; Accepted 2 April 2012

Academic Editor: Michael H√ľnerbein

Copyright © 2012 Keiko Takeuchi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A 52-year-old Japanese woman who was eventually diagnosed with primary follicular lymphoma of the duodenum showed atypical endoscopic features, namely, erosions with peripheral whitish edematous mucosa. Initial biopsy specimens taken from the erosions revealed insufficient numbers of lymphoma cells for histological diagnosis. Subsequent biopsy specimens from the peripheral mucosa containing the whitish enlarged villi showed infiltration of the lymphoma cells forming lymphoid follicles, which led us to the appropriate diagnosis. This case indicates that endoscopists should take biopsy samples from the peripheral mucosa with whitish enlarged villi rather than erosions in the rare instances that erosions appear as the main macroscopic feature of intestinal follicular lymphoma.