TY - JOUR A2 - Van der Meer, J. W. M. AU - Fargetti, Simone AU - Goldenstein-Schainberg, Claudia AU - Silva Abreu, Andressa AU - Fuller, Ricardo PY - 2012 DA - 2012/11/25 TI - Refractory Gout Attack SP - 657694 VL - 2012 AB - Refractory gout attack is an uncommon problem, since gout flares are usually self-limited. This clinical condition is characterized by serum uric acid higher than 6 mg/Dl or continuous manifestations of recurrent flares, chronic arthritis, and increased tophi. We report in this paper a 69-year-old man with a polyarticular and protracted gout attack, despite usual treatment and low urate sera levels. In order to manage this problem, we reviewed gout pathophysiology and developed a therapeutic solution based on benzbromarone pharmacokinetics. We also review herein new options for gout treatment that could be used in similar cases. SN - 1687-9627 UR - https://doi.org/10.1155/2012/657694 DO - 10.1155/2012/657694 JF - Case Reports in Medicine PB - Hindawi Publishing Corporation KW - ER -