A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain

Table 1

Endocrine examinations on admission.

TSH	1.7	𝜇U/mL	(0.4–3.8)
FT3	2.1	pg/mL	(2.0–3.4)
FT4	1.2	ng/dL	(0.9–1.6)
IGF-1	201.0	ng/mL	(94–261)*
ACTH	28.0	pg/mL	(0–60)
Cortisol	11.2	μg/dL	(4.5–24.5)
DHEA-S	99.4	𝜇g/dL	(41.3–218.2)
Urinary cortisol	43.0	𝜇g/day	(10–100)
LH	1.1	mIU/mL	(1.7–11.2)
FSH	1.1	mIU/mL	(2.1–18.6)
Total testosterone	1.0	ng/mL	(2.7–10.7)
Free testosterone	4.5	pg/mL	(7.7–21.6)

( ): normal range.
*Age-specific normal range.