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Case Reports in Medicine
Volume 2012, Article ID 748202, 5 pages
http://dx.doi.org/10.1155/2012/748202
Case Report

Association between a Primitive Brain Tumor and Cerebral Aspergillosis

1Laboratoire de Neuropathologie Escourolle, Institut du Cerveau et de la Moelle épinière, Université Pierre et Marie Curie, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, 47-83 boulevard de l’Hôpital, 75651 Paris cedex 13, France
2Service de Neuroradiologie, Institut du Cerveau et de la Moelle épinière, Université Pierre et Marie Curie, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, 47-83 boulevard de l’Hôpital, 75651 Paris cedex 13, France

Received 18 September 2011; Revised 15 November 2011; Accepted 8 December 2011

Academic Editor: Jacques F. Meis

Copyright © 2012 Siegfried Hélage et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cerebral aspergillosis is a rare pathology of poor prognosis in spite of the use of adapted antifungal treatments. This infection of the central nervous system is generally the complication of an invasive aspergillosis with hematogenic scattering from pulmonary focal spots. It can arise in immunocompetent patients treated with prolonged corticotherapy or chemoradiotherapy for cancer. A case of lethal cerebral aspergillosis in a patient with an infiltrative glioma treated with corticotherapy and radiotherapy is reported. Clinicopathological aspects and therapeutic approach are described.