Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Medicine
Volume 2013, Article ID 194542, 4 pages
http://dx.doi.org/10.1155/2013/194542
Case Report

Graves’ Disease Causing Pancytopenia and Autoimmune Hemolytic Anemia at Different Time Intervals: A Case Report and a Review of the Literature

1Department of Internal Medicine, Dayton Veterans Affair Medical Center, Boonshoft School of Medicine, Wright State University, 4100 West Third Street, Dayton, OH 45428, USA
2Department of Hematology and Oncology, Dayton Veterans Affair Medical Center, Boonshoft School of Medicine, Wright State University, 4100 West Third Street, Dayton, OH 45428, USA
3Department of Pathology, Dayton Veterans Affair Medical Center, Boonshoft School of Medicine, Wright State University, 4100 West Third Street, Dayton, OH 45428, USA
4Department of Endocrinology and Metabolism, Dayton Veterans Affair Medical Center, Boonshoft School of Medicine, Wright State University, 4100 West Third Street, Dayton, OH 45428, USA

Received 8 July 2013; Accepted 24 September 2013

Academic Editor: Masahiro Kohzuki

Copyright © 2013 Peyman Naji et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. C. Ford and J. M. Carter, “The haematology of hyperthyroidism: abnormalities of erythrocytes, leucocytes, thrombocytes and haemostasis,” Postgraduate Medical Journal, vol. 64, no. 756, pp. 735–742, 1988. View at Google Scholar · View at Scopus
  2. E. S. Orwoll and R. L. Orwoll, “Hematologic abnormalities in patients with endocrine and metabolic disorders,” Hematology/Oncology Clinics of North America, vol. 1, no. 2, pp. 261–279, 1987. View at Google Scholar · View at Scopus
  3. J. A. Franklyn and K. Boelaert, “Thyrotoxicosis,” The Lancet, vol. 379, no. 9821, pp. 1155–1166, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. K. Boelaert, P. R. Newby, M. J. Simmonds et al., “Prevalence and relative risk of other autoimmune diseases in subjects with autoimmune thyroid disease,” The American Journal of Medicine, vol. 123, no. 2, pp. 183.e1–183.e9, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. A. G. Gianoukakis, M. J. Leigh, P. Richards et al., “Characterization of the anaemia associated with Graves' disease,” Clinical Endocrinology, vol. 70, no. 5, pp. 781–787, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. M. O. Hegazi and S. Ahmed, “Atypical clinical manifestations of Graves' disease: an analysis in depth,” Journal of Thyroid Research, vol. 2012, Article ID 768019, 8 pages, 2012. View at Publisher · View at Google Scholar
  7. E. Chiang and C. D. Packer, “Concurrent reactive arthritis, Graves' disease, and warm autoimmune hemolytic anemia: a case report,” Cases Journal, vol. 2, no. 8, article 6988, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. Y. C. Chee, D. S. Gill, and S. C. Poh, “Hyperthyroidism and autoimmune hemolytic anemia—a case report,” Medical Journal of Malaysia, vol. 33, no. 2, pp. 154–155, 1978. View at Google Scholar · View at Scopus
  9. D. O'Brien, D. J. Lyons, and J. F. Fielding, “A case of Graves' disease associated with autoimmune haemolytic anaemia,” Irish Journal of Medical Science, vol. 158, no. 6, article 155, 1989. View at Google Scholar · View at Scopus
  10. T. Ogihara, H. Katoh, H. Yoshitake, S. Iyori, and I. Saito, “Hyperthyroidism associated with autoimmune hemolytic anemia and periodic paralysis: a report of a case in which antihyperthyroid therapy alone was effective against hemolysis,” Japanese Journal of Medicine, vol. 26, no. 3, pp. 401–403, 1987. View at Google Scholar · View at Scopus
  11. T. Ushiki, M. Masuko, K. Nikkuni et al., “Successful remission of Evans syndrome associated with Graves' disease by using propylthiouracil monotherapy,” Internal Medicine, vol. 50, no. 6, pp. 621–625, 2011. View at Google Scholar · View at Scopus
  12. M. Yashiro, H. Nagoshi, Y. Kasuga et al., “Evans's syndrome associated with Graves' disease,” Internal Medicine, vol. 35, no. 12, pp. 987–990, 1996. View at Google Scholar · View at Scopus
  13. M. Crowther, Y. L. T. Chan, I. K. Garbett, W. Lim, M. A. Vickers, and M. A. Crowther, “Evidence-based focused review of the treatment of idiopathic warm immune hemolytic anemia in adults,” Blood, vol. 118, no. 15, pp. 4036–4040, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Hegazi, R. Kumar, Z. Bitar, and E. Ibrahim, “Pancytopenia related to Graves' disease,” Annals of Saudi Medicine, vol. 28, no. 1, pp. 48–49, 2008. View at Google Scholar · View at Scopus
  15. C. S. P. Lima, D. E. Z. Wittmann, V. Castro et al., “Pancytopenia in untreated patients with Graves' disease,” Thyroid, vol. 16, no. 4, pp. 403–409, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. B. Shaw and A. B. Mehta, “Pancytopenia responding to treatment of hyperthyroidism: a clinical case and review of the literature,” Clinical and Laboratory Haematology, vol. 24, no. 6, pp. 385–387, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. A. L. Talansky, P. Schulman, V. P. Vinciguerra, D. Margouleff, D. R. Budman, and T. J. Degnan, “Pancytopenia complicating Graves' disease and drug-induced hypothyroidism,” Archives of Internal Medicine, vol. 141, no. 4, pp. 544–545, 1981. View at Google Scholar · View at Scopus
  18. M. Duquenne, D. Lakomsky, J. C. Humbert, S. Hadjadj, G. Weryha, and J. Leclere, “Resolutive pancytopenia with effective treatment of hyperthyroidism,” Presse Medicale, vol. 24, no. 17, pp. 807–810, 1995. View at Google Scholar · View at Scopus
  19. P. K. Das, D. Wherrett, and Y. Drore, “Remission of aplastic anemia induced by treatment for Graves disease in a pediatric patient,” Pediatric Blood and Cancer, vol. 49, no. 2, pp. 210–212, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. D. S. Cooper, “Antithyroid drugs,” The New England Journal of Medicine, vol. 352, no. 9, pp. 905–917, 2005. View at Publisher · View at Google Scholar · View at Scopus