Case Report

A Case of Granulomatosis with Polyangiitis (Wegener’s Granulomatosis) Presenting with Marked Inflamed Tracheobronchial Mucosa

Figure 3

Histologic findings from the transbronchial biopsy specimens obtained from the right second carina ((a), (b)) and the nodule on the apex of the right lung ((c), (d)) using hematoxylin and eosin stains. Granuloma formation accompanied by abundant inflammatory cells ((a), arrow) and many multinucleated giant cells was found in the right second carina, surrounded by neutrophil-infiltrated microabscess on bronchial mucosa ((a), arrow head). The histology of the nodules on the right upper lobe also showed inflammatory cells including nodular necrotizing foci (c) and multinucleated giant cells (d). Obvious vasculitis was not found.
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(a)
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(b)
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(c)
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(d)