Autoimmune Hepatitis Triggered by Anti-TNF-𝜶 Therapy

Table 1

Reported cases of psoriasis with AIH triggered by anti-TNF-α therapy.

No.	Sex	Age (years)	Anti-TNF-α	Time to liver damage; Number of doses	Expressed autoantibodies	Treatment	Time to the resolution of liver damage
1 [4]	Female	53	Infliximab	26 weeks; 6	ANA; Anti-ds DNA; ASMA	Fluocortolone	12 weeks
2 [5]	Female	22	Infliximab	6 weeks; 2	ANA	Prednisone; Azathioprine	NA
3 [6]	Male	37	Infliximab	6 weeks; 3	ANA; Anti-ds DNA; ASMA	Cessation only	2 months
4 [7]	Male	51	Infliximab	One month; 3	ANA; Anti-ds DNA; AMA; Anti-cardiolipin antibodies	Azathioprine; Corticosteroids; Ursodeoxycholic acid	NA
5 [8]	Female	36	Adalimumab	3 months; 6	ANA; Anti-ds DNA	Prednisone; Azathioprine	2 months
6 [8]	Female	47	Infliximab	10 weeks; 3	ANA; ASMA	Prednisolone	3 months
7 (our case)	Female	52	Adalimumab	2 months; 6	ANA	Prednisolone	2 months

ANA: anti-nuclear antibody, Anti-ds DNA: anti-double stranded DNA antibody, ASMA: anti-smooth muscle antibody, AMA: anti-mitochondrial antibody, PBC: primary biliary cirrhosis, and NA: not available.