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Case Reports in Medicine
Volume 2013, Article ID 570921, 4 pages
Case Report

Acute Glomerulonephritis in a Child with Chlamydia pneumoniae Infection: A Case Report

1Pediatric Acute and Emergency Operative Unit, Policlinico-Vittorio-Emanuele University Hospital, University of Catania, Via Plebiscito 628, 95100 Catania, Italy
2Pediatric Consultant of the Regional Institution, ASP3, 95100 Catania, Italy
3Department of Internal Medicine and Systemic Diseases, Division of Medicine for Job, University of Catania, 95100 Catania, Italy
4Pediatric Operative Unit, Gravina and Santo Pietro of Caltagirone Hospital, 95100 Catania, Italy
5Division of Infectious Diseases, Thomas Jefferson University, Philadelphia, PA, USA

Received 6 April 2013; Accepted 5 June 2013

Academic Editor: Ting Fan Leung

Copyright © 2013 Giovanna Vitaliti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Infectious diseases seem to be an important and independent risk factor for renal failure, but the underlying mechanism of renal involvement during some kinds of infectious diseases is still unclear, even if the literature data report immunomediated and/or autoimmune mechanisms to explain the pathogenic relationship between the two diseases. In paediatric patients, Chlamydia pneumoniae is a rare cause of renal complications and it may manifest in several ways, mainly involving the respiratory system, even if also renal and glomerulalr complications, have been described. Case Diagnosis/Treatment. Herein we report a case of a 3-year-old child who developed an acute glomerulonephritis that was chronologically, clinically, and biologically related to a previous Chlamydia pneumoniae infection. On our knowledge, in the literature it is the youngest patient with renal involvement during course of Chlamydia pneumoniae infection ever reported. Conclusions. The present case supports the hypothesis of a rather close causal relationship between this infective agent and renal and glomerular symptoms occurred in this child, during an acute episode of respiratory disease.