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Case Reports in Medicine
Volume 2013 (2013), Article ID 747431, 4 pages
Case Report

Cerebral Venous Thrombosis Revealing Primary Sjögren Syndrome: Report of 2 Cases

1Department of Neurological and Psychiatric Sciences, Sapienza University of Rome, Viale dell'Università 30, 00185 Rome, Italy
2Department of Physical Medicine and Rehabilitation, Sapienza University of Rome, P.le Aldo Moro, 5, 00185 Rome, Italy

Received 11 October 2012; Revised 3 December 2012; Accepted 17 December 2012

Academic Editor: W. Zidek

Copyright © 2013 A. Mercurio et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Sjögren syndrome (SS) is an autoimmune disease of the exocrine glands, characterized by focal lymphocytic infiltration and destruction of these glands. Neurologic complications are quite common, mainly involving the peripheral nervous system (PNS). The most common central nervous system (CNS) manifestations are myelopathy and microcirculation vasculitis. However, specific diagnostic criteria for CNS SS are still lacking. We report two cases of primary SS in which the revealing symptom was cerebral venous thrombosis (CVT) in the absence of genetic or acquired thrombophilias.