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Case Reports in Medicine
Volume 2014, Article ID 206152, 3 pages
Case Report

Management of Varicella Gangrenosa: A Life-Threatening Condition from Chickenpox

1Department of Surgery, Orbis Medical Centre, P.O. Box 5500, 6130 MB Sittard, The Netherlands
2Department of Surgery, Atrium Medical Centre, Heerlen, The Netherlands
3Department of Pediatrics, Haga Hospital, The Hague, The Netherlands

Received 27 September 2014; Accepted 4 November 2014; Published 19 November 2014

Academic Editor: Luis García-Marcos

Copyright © 2014 Judith P. M. Schots et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Varicella gangrenosa, in which gangrenous ulceration of the skin and/or deeper tissues is seen, is a rare but alarming complication of Varicella infection. An early surgical intervention is generally advised, especially in case of sepsis and/or the presence of large necrotic lesions. We describe a case of a previously healthy 12-month-old boy presenting with sepsis due to Varicella gangrenosa. He presented with moderate lesions of moist gangrene. We treated our patient initially with antibiotics (ceftriaxone and metronidazole) and later on flucloxacillin and antiviral therapy (acyclovir) whereupon his condition rapidly improved and all skin lesions healed entirely. This report highlights the possibility of conservative treatment and emphasizes the significance of acyclovir in the management of chickenpox complicated by moist gangrene due to bacterial superinfection.