Cholangiocarcinoma Presenting with Hypercalcemia and Thrombocytopenia
Figure 1
(a) CT scan, cm size hypoattenuating multinodular tumor mainly filling the right lobe of the liver with irregular boundaries. (b) MR, T2-weighted images as a slightly hyperintense area with contrast enhancement of peripheral zone being liable to confluent multiple lesions in the right lobe of liver. (c) Fluorodeoxyglucose-positron emission tomography (FDG-PET) showed 10.7 of a standardized uptake value for FDG in CC of liver. (d) Tumor cells diffusely formed ductal structures in fibrotic stroma and have a big hyperchromatic nucleus in narrow cytoplasm, H&E, 200. (e) Tumor cells diffusely replaced the liver parenchyma and formed ductal structures in fibrotic stroma which were positively stained for cytokeratin 19 immunoreaction, 200. (f) Tumor cells diffusely replaced the liver parenchyma and formed ductal structures in fibrotic stroma which were positively stained for cytokeratin 7 immunoreaction 200.
