A New Case of Syringocystadenocarcinoma Papilliferum: A Rare Pathology for a Wide-Ranging Comprehension
Figure 3
Fluorescence microscopy analysis of the staminal property of syringocystadenocarcinoma papilliferum. Immunofluorescent staining demonstrates anti-CD133 (in red) and anti-CD44 (in green) antibodies; the nuclei are contrasted by DAPI (in blue). (a) The tumoral squamous portion shows membranous CD44 overexpression (original magnification ×200). (b) The transition area presents squamous budding with decreasing of CD44 positivity but increasing of nuclear-cytoplasmic CD133 expression (original magnification ×200). (c) Bifront-like staining showing CD44 more represented in the squamous area and CD133 stronger in the papillary component (original magnification ×200). (d) Overview of CD133 positive-cystic and papillary structures (original magnification ×100).
