One Patient, Two Uncommon B-Cell Neoplasms: Solitary Plasmacytoma following Complete Remission from Intravascular Large B-Cell Lymphoma Involving Central Nervous System
Figure 2
(a) Intravascular large B-cell lymphoma of brain. Hematoxylin and eosin (H/E) staining highlights intravascular large B-cell lymphoma in the brain, featuring large cells with moderate pleomorphism, vesicular chromatin, and prominent nucleoli. (b) Intravascular large B-cell lymphoma of brain. Immunohistochemistry confirms the B-cell lineage of the intravascular large cell lymphoma, being CD20+ CD3− and showing a high proliferation fraction by staining for Ki67. It displays a germinal centre phenotype by Hans’ criteria, being CD10− bcl6+ MUM1− and lacks blimp1 expression.
