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Case Reports in Medicine
Volume 2014, Article ID 637492, 7 pages
http://dx.doi.org/10.1155/2014/637492
Case Report

Mucormycosis in Patients with Inflammatory Bowel Disease: Case Series and Review of the Literature

1Division of Infectious Diseases, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
2Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
3Altru Medical Center, Grand Forks, ND 58201, USA
4Division of Infectious Diseases, Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55902, USA

Received 20 February 2014; Accepted 22 March 2014; Published 27 April 2014

Academic Editor: Yasuhiko Sugawara

Copyright © 2014 Maheen Z. Abidi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Mucormycosis is a rare and often fatal invasive fungal infection mostly seen in immune-compromised individuals. A high index of clinical suspicion is necessary, so that effective preemptive therapy can be started, as timely intervention is crucial. In this series we present three cases of invasive mucormycosis in patients with underlying inflammatory bowel disease that had received therapy with immunomodulators prior to the infection. All three had varied clinical manifestations. We also review the literature of invasive mucormycosis in patients with inflammatory bowel disease.