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Case Reports in Medicine
Volume 2015, Article ID 278376, 6 pages
Case Report

Histopathologic Finding of Both Gastric and Respiratory Epithelia in a Lingual Foregut Cyst

1Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA
2Department of Pathology, Children’s Hospital Los Angeles, Los Angeles, CA 90027, USA
3Division of Otolaryngology-Head and Neck Surgery, Children’s Hospital Los Angeles, Los Angeles, CA 90027, USA

Received 25 March 2015; Accepted 16 July 2015

Academic Editor: Li Jin

Copyright © 2015 Yangfan Luo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Foregut cysts are uncommon, mucosa-lined congenital lesions that may occur anywhere along the gastrointestinal or respiratory tract and typically present within the first year of life. Although infrequent, these cysts may generate feeding or respiratory difficulties depending on the size and location of the lesion. Foregut cysts of the oral cavity are rarely seen and of those cases localized to the tongue are even more uncommon. We describe a 4-month-old girl with a foregut cyst involving the floor of mouth and anterior tongue. Subsequent histologic analysis demonstrated a cyst lined with both gastric and respiratory epithelia. This case represents an extremely rare finding of both gastric and respiratory epithelia lined within a single cystic structure in the tongue. Although a very rare finding, a foregut cyst should be on the differential diagnosis of any lesion involving the floor of mouth or tongue in an infant or child.