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Case Reports in Medicine
Volume 2015, Article ID 479625, 5 pages
http://dx.doi.org/10.1155/2015/479625
Case Report

Intramucosal Signet Ring Cell Gastric Cancer Diagnosed 15 Months after the Initial Endoscopic Examination

1Department of Gastroenterology, Shinmatsudakai Atago Hospital, Kochi 780-0051, Japan
2Department of Endoscopic Diagnostics and Therapeutics, Kochi Medical School, Kochi University, Nankoku 783-8505, Japan
3Department of Gastroenterological Surgery, Kochi Health Sciences Center, Kochi 781-0111, Japan
4Department of Diagnostic Pathology, Kochi Health Sciences Center, Kochi 781-0111, Japan
5Department of Pathology, Kochi Medical School, Kochi University, Nankoku 783-8505, Japan

Received 27 March 2015; Accepted 8 June 2015

Academic Editor: Michael Hünerbein

Copyright © 2015 Keisuke Taniuchi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The size and shape of intramucosal signet ring gastric cancer in this case remained endoscopically unchanged for 15 months. Laparoscopy-assisted distal gastrectomy was performed, and immunohistochemical analysis revealed Ki-67 and p53 mutations to be negative in this case. Signet ring gastric cancer has long been thought to confer a worse prognosis than other forms of gastric cancer; however, our case did not progress to advanced gastric cancer for 15 months.