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Case Reports in Medicine
Volume 2015, Article ID 592170, 4 pages
http://dx.doi.org/10.1155/2015/592170
Case Report

Dual Effect of Ziconotide in Primary Erythromelalgia

1Pain Therapy Unit, Department of Hematology and Oncology, Pugliese-Ciaccio Hospital, Catanzaro, Italy
2Department of Pharmacy and Health and Nutritional Sciences, University of Calabria, Italy
3Molecular Biology Unit, Department of Hematology and Oncology, Pugliese-Ciaccio Hospital, Catanzaro, Italy

Received 15 July 2015; Revised 20 October 2015; Accepted 21 October 2015

Academic Editor: Piotr K. Janicki

Copyright © 2015 Rosario Russo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Erythromelalgia (EM) is a rare disabling clinical syndrome more commonly known to affect the lower extremities. There is no single effective treatment for this disease that often requires a multidisciplinary approach. Herein, we report the case of a 31-year-old woman affected by primary erythromelalgia who was successfully treated with intrathecal Ziconotide. We also observed an unexpected result following therapy with Ziconotide. The legs and feet of the patient that at the time of admission were swollen and tumefied dramatically improved after one week of the drug administration.