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Case Reports in Medicine
Volume 2015, Article ID 971321, 3 pages
Case Report

Deep Venous Thrombosis with Pulmonary Embolism Related to IVIg Treatment: A Case Report and Literature Review

University of South Florida Morsani College of Medicine, 12901 Bruce B Downs Boulevard, MDC Box 19, Room L1041, Tampa, FL 33612, USA

Received 26 January 2015; Revised 6 May 2015; Accepted 7 May 2015

Academic Editor: Masahiro Kohzuki

Copyright © 2015 Michael T. Flannery and Deborah Humphrey. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


IVIg therapy has potentially been related to arterial and venous therapy. We performed an Ovid review focusing on IVIg and thrombotic events. While a few case reports were reviewed case series and case control studies were particularly reviewed in relation to thrombotic events. Outcomes demonstrate a correlation between underlying cardiovascular risk factors with predominately arterial events which typically occurred within 4–24 hours of infusion. While venous events occurred less commonly they were associated with traditional risk factors and occurred later, typically, 1–7 days following infusion of IVIg. Potential causation of thrombotic events was discussed.