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Case Reports in Medicine
Volume 2016, Article ID 3920516, 4 pages
Case Report

Rosai-Dorfman Disease Involving Multiple Organs: An Unusual Case with Poor Prognosis

Department of Dermatology, Joseph Raseta Befelatanana Hospital, 101 Antananarivo, Madagascar

Received 19 July 2016; Accepted 13 October 2016

Academic Editor: Tomás A. Salerno

Copyright © 2016 Fandresena Arilala Sendrasoa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Rosai-Dorfman disease is a rare, benign histiocytic proliferative disorder that usually affects the lymph nodes. Although extranodal involvement has been reported in diverse sites, manifestation in the cardiovascular system is extremely rare. Specifically, cardiac involvement in Rosai-Dorfman disease is an extraordinarily infrequent event. We describe a case of a 36-year-old female who presented Rosai-Dorfman disease of multiple organs including the heart, with poor prognosis.