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Case Reports in Medicine
Volume 2016, Article ID 6723575, 3 pages
Case Report

A Tongue Lesion as a Sign of a Systemic Disease

1Third Department of Medical Oncology, Hygeia Hospital, 15123 Athens, Greece
2Johns Hopkins University Internship Program, Baltimore, MD 21218, USA
3Intensive Care Unit, Hygeia Hospital, 15123 Athens, Greece
4First Department of Cardiology, Hygeia Hospital, 15123 Athens, Greece
5Department of Otolaryngology, Hygeia Hospital, 15123 Athens, Greece
6Department of Pathology, Hygeia Hospital, 15123 Athens, Greece

Received 22 October 2015; Revised 4 January 2016; Accepted 10 January 2016

Academic Editor: Mamede de Carvalho

Copyright © 2016 Chrysoula I. Liakou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Amyloidosis is the extracellular fibril deposition of a variety of proteins, many of which circulate as plasma ingredients. It is a disease difficult to identify due to its nonspecific symptoms and manifestations. Amyloidosis of the tongue, either isolated or part of the systemic disease, is rare and its features resemble those of a tumor. We report the case of a patient with amyloidosis who presented with a tongue lesion, weakness, nonspecific arthritis, and dyspnea on exertion that resulted in multiorgan system failure.