Neuroendocrine Differentiation in Breast Cancer: Clinicopathological Significance of Bcl-2 Positive Solid Papillary Carcinoma

Figure 3

(a) A solid tumor 25 × 30 × 25 mm in size whose surface is sharply demarcated from the surrounding tissue (arrow) is seen at the cut surface of the specimen. Both necrosis and hemorrhage are present. (b) Sections of paraffin-embedded tissue were prepared and stained with HE double stain for light microscopic observation. A histological section reveals intraductal carcinoma showing a solid papillary growth pattern and the neoplastic lesion is encapsulated by bands of dense fibrosis (HE stain, original magnification ×40). (c) Nuclear palisading around fibrovascular cores was found (HE stain, original magnification ×400).