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Case Reports in Medicine
Volume 2017, Article ID 5032630, 5 pages
Case Report

Systemic Cystic Angiomatosis Mimicking Metastatic Cancer: A Case Report and Review of the Literature

1Department of Internal Medicine, Maimonides Medical Center, Brooklyn, NY, USA
2Department of Hematology and Oncology, Maimonides Cancer Center, Brooklyn, NY, USA
3Department of Pathology, Maimonides Medical Center, Brooklyn, NY, USA

Correspondence should be addressed to Yiwu Huang; gro.demsedinomiam@gnauhj

Received 28 May 2017; Accepted 7 August 2017; Published 11 September 2017

Academic Editor: Isidro Machado

Copyright © 2017 Vivek Kumar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Systemic cystic angiomatosis is a rare benign disorder due to the maldeveloped vascular and lymphatic system with less than 50 cases reported in literature so far. We report here a case of systemic cystic angiomatosis (SCA) with multisystem involvement affecting the neck, thyroid, thoracic cavity, and skeletal system. The patient initially presented in her 4th decade of life with isolated lymphangioma in the neck requiring surgery. However, she experienced full-blown manifestations of SCA in her 6th decade which closely mimicked metastatic cancer. The diagnosis of SCA could only be established after multiple biopsies. The radiological and histological features of SCA with its course over 31 years in this patient have been described.