Case Report

Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia

Table 1

Table of trends and clinical timeline of events, following trends from 2007 to 2011.

Lab trends seen in case of multisystem GPA

Date%Cr mg/dLPlts (×106)Peak troponin IEvent

8/11/200711.22.13633.6Initial arrival (1st troponin 2.63 ng/ml before Vtach and cardioversion), peak after cardioversion was 33.6 ng/ml given hydrocortisone 100 mg iv TID (Stress dose), hydroxyurea 1500 mg, and HD #1

8/12/20071.2783.24Given plasmapheresis session #1 and HD #2, started on prednisone 60 mg

8/13/20070.255.70.6083.11Second echo checked

8/14/20076.10.5772.59

8/15/20074.10.6192.54Last troponin checked at first hospitalization

8/16/200750.545

8/17/20076.40.728

8/18/20075.20.58First cyclophosphamide dose given 750 mg

8/21/20070.256.60.428Third echo checked

8/24/20073.10.432

9/4/20070.55

9/18/20071.60.351

8/12/20080.551.420.367Early 2008 second cyclophosphamide course, switched to IV Rituxan and then Cellcept

1/20/20110.550.870.4Small pericardial effusion seen on Echo, switching to maintenance methotrexate

Cr = serum creatinine, EF = ejection fraction, HD = hemodialysis, IV = intravenous, and Plts = platelets.