Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia
Table 1
Table of trends and clinical timeline of events, following trends from 2007 to 2011.
Lab trends seen in case of multisystem GPA
Date
%
Cr mg/dL
Plts (×106)
Peak troponin I
Event
8/11/2007
11.2
2.136
33.6
Initial arrival (1st troponin 2.63 ng/ml before Vtach and cardioversion), peak after cardioversion was 33.6 ng/ml given hydrocortisone 100 mg iv TID (Stress dose), hydroxyurea 1500 mg, and HD #1
8/12/2007
1.278
3.24
Given plasmapheresis session #1 and HD #2, started on prednisone 60 mg
8/13/2007
0.25
5.7
0.608
3.11
Second echo checked
8/14/2007
6.1
0.577
2.59
8/15/2007
4.1
0.619
2.54
Last troponin checked at first hospitalization
8/16/2007
5
0.545
8/17/2007
6.4
0.728
8/18/2007
5.2
0.58
First cyclophosphamide dose given 750 mg
8/21/2007
0.25
6.6
0.428
Third echo checked
8/24/2007
3.1
0.432
9/4/2007
0.55
9/18/2007
1.6
0.351
8/12/2008
0.55
1.42
0.367
Early 2008 second cyclophosphamide course, switched to IV Rituxan and then Cellcept
1/20/2011
0.55
0.87
0.4
Small pericardial effusion seen on Echo, switching to maintenance methotrexate
Cr = serum creatinine, EF = ejection fraction, HD = hemodialysis, IV = intravenous, and Plts = platelets.