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Case Reports in Medicine
Volume 2018, Article ID 1864962, 6 pages
Case Report

Recurrent Syncope, a Clue in Amyloid Cardiomyopathy

Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA

Correspondence should be addressed to Ricardo J. Pagán; ude.oyam@odracir.nagap

Received 26 October 2017; Revised 8 December 2017; Accepted 26 December 2017; Published 28 January 2018

Academic Editor: Grigrios Korosoglou

Copyright © 2018 Julian A. Marin-Acevedo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Infiltrative cardiomyopathies include a variety of disorders that lead to myocardial thickening resulting in a constellation of clinical manifestations and eventually heart failure that could be the first clue to reach the diagnosis. Among the more described infiltrative diseases of the heart is amyloid cardiomyopathy. The disease usually presents with subtle, nonspecific symptoms. Herein, we illustrate a case of recurrent syncope as the initial presenting symptom for systemic amyloid with polyneuropathy and cardiomyopathy as a cause of syncope. The article illustrates the role of advanced cardiac imaging in the diagnosis of the disease with a focused literature review. We also highlight the role of early, shared decision-making between patient, family, and medical team in the management of cardiac amyloidosis.