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Case Reports in Medicine
Volume 2018, Article ID 2573657, 4 pages
https://doi.org/10.1155/2018/2573657
Case Report

Haploidentical Stem Cell Transplantation: A Gateway to Infrequent Availability of HLA-Matched Related Donors

1Department of Internal Medicine, Seton Hall University (St Francis) Program, Trenton, USA
2Department of Internal Medicine, University at Buffalo (Catholic Health System-Sisters of Charity) Program, Buffalo, USA
3Department of Internal Medicine, Allegheny Health Network, Pennsylvania, USA
4Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan
5King Faisal University Hospital and Research Center, Riyadh, Saudi Arabia
6Department of Medicine, Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA

Correspondence should be addressed to Hafiz Muhammad Aslam; moc.liamtoh@meelasmalsadammahum

Received 18 May 2018; Revised 19 July 2018; Accepted 12 August 2018; Published 10 September 2018

Academic Editor: Simone Cesaro

Copyright © 2018 Hafiz Muhammad Aslam et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. A. Kernan, G. Bartsch, R. C. Ash et al., “Analysis of 462 transplantations from unrelated donors facilitated by the national marrow donor program,” New England Journal of Medicine, vol. 328, no. 9, pp. 593–602, 1993. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Dominietto, A. M. Raiola, M. T. van Lint et al., “Factors influencing haematological recovery after allogeneic haemopoietic stem cell transplants: graft-versus-host disease, donor type, cytomegalovirus infections and cell dose,” British Journal of Haematology, vol. 112, no. 1, pp. 219–227, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. D. J. Weisdorf, “Allogeneic bone marrow transplantation for chronic myelogenous leukemia: comparative analysis of unrelated versus matched sibling donor transplantation,” Blood, vol. 99, no. 6, pp. 1971–1977, 2002. View at Publisher · View at Google Scholar · View at Scopus
  4. J. Mattsson, O. Ringdén, and R. Storb, “Graft failure after allogeneic hematopoietic cell transplantation,” Blood and Marrow Transplantation, vol. 14, no. 1, pp. 165–170, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. A. E. DeZern, M. Zahurak, H. Symons, K. Cooke, R. J. Jones, and R. A. Brodsky, “Alternative donor transplantation with high-dose post-transplantation cyclophosphamide for refractory severe aplastic anemia,” Biology of Blood and Marrow Transplantation, vol. 23, no. 3, pp. 498–504, 2017. View at Publisher · View at Google Scholar · View at Scopus
  6. L. J. Han, Y. Wang, Z.-P. Fan et al., “Haploidentical transplantation compared with matched sibling and unrelated donor transplantation for adults with standard-risk acute lymphoblastic leukaemia in first complete remission,” British Journal of Haematology, vol. 179, no. 1, pp. 120–130, 2017. View at Publisher · View at Google Scholar · View at Scopus
  7. W. A. Bethge, M. Haegele, C. Faul et al., “Haploidentical allogeneic hematopoietic cell transplantation in adults with reduced-intensity conditioning and CD3/CD19 depletion: fast engraftment and low toxicity,” Experimental Hematology, vol. 34, no. 12, pp. 1746–1752, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. P. Chiusolo, G. Bug, A. Olivieri et al., “A modified post-transplant cyclophosphamide regimen, for unmanipulated haploidentical marrow transplantation, in acute myeloid leukemia: a multicenter study,” Biology of Blood and Marrow Transplantation, vol. 24, no. 6, pp. 1243–1249, 2018. View at Publisher · View at Google Scholar · View at Scopus
  9. S. R. McCurdy, C. G. Kanakry, H.-L. Tsai et al., “Grade II acute graft-versus-host disease and higher nucleated cell graft dose improve progression-free survival after HLA-haploidentical transplant with post-transplant cyclophosphamide,” Biology of Blood and Marrow Transplantation, vol. 24, no. 2, pp. 343–352, 2018. View at Publisher · View at Google Scholar · View at Scopus
  10. I. Esteves, C. Bonfim, R. Pasquini et al., “Haploidentical BMT and post-transplant Cy for severe aplastic anemia: a multicenter retrospective study,” Bone Marrow Transplantation, vol. 50, no. 5, p. 685, 2015. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Miao, X. Zhang, T. Xu et al., “Haploidentical hematopoietic stem cell transplantation for acquired severe aplastic anemia,” American Society of Hematology, vol. 126, no. 23, p. 3227, 2015. View at Google Scholar
  12. L.-P. Xu, S. Jin, S.-Q. Wang et al., “Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant,” Journal of Hematology and Oncology, vol. 10, no. 1, p. 25, 2017. View at Publisher · View at Google Scholar · View at Scopus
  13. J. Sierra, B. Storer, J. A. Hansen et al., “Unrelated donor marrow transplantation for acute myeloid leukemia: an update of the Seattle experience,” Bone Marrow Transplantation, vol. 26, no. 4, pp. 397–404, 2000. View at Publisher · View at Google Scholar
  14. P. V. O’Donnell, L. Luznik, R. J. Jones et al., “Nonmyeloablative bone marrow transplantation from partially HLA-mismatched related donors using posttransplantation cyclophosphamide,” Biology of Blood and Marrow Transplantation, vol. 8, no. 7, pp. 377–386, 2002. View at Publisher · View at Google Scholar · View at Scopus
  15. D. E. Gladstone, A. A. Zachary, E. J. Fuchs et al., “Partially mismatched transplantation and human leukocyte antigen donor-specific antibodies,” Biology of Blood and Marrow Transplantation, vol. 19, no. 4, pp. 647–652, 2013. View at Publisher · View at Google Scholar · View at Scopus